These Substances may Detoxify Methanol
Cysteine may detoxify Methanol-
N-Acetyl-Cysteine (NAC) may reduce the toxicity of Methanol in the Brain.
Enzymes–Alcohol Dehydrogenase facilitates the detoxification of Methanol within the Liver (it catalyzes the conversion of Methanol to Formaldehyde).
Folic Acid may reduce the toxicity of Methanol. Degradation of Formic Acid (Methanol’s ultimate metabolic end-product) is dependent on adequate Folic Acid. Persons who are deficient in Folic Acid may experience more severe symptoms of Methanol toxicity due to increased accumulation of Formic Acid in the body. references
Vitamin C may accelerate the conversion of Methanol to Formaldehyde and may reduce body movement abnormalities caused by Methanol. references
Vitamin E may inhibit the ability of Methanol to damage the Liver.
A 10% ethanol solution administered intravenously is a safe and effective antidote for severe methanol poisoning– Ethanol as antidote
Competitively blocks the formation of toxic metabolites in toxic alcohol ingestions by having a higher affinity for the enzyme Alcohol Dehydrogenase (ADH). Its chief application is in methanol and ethylene glycol ingestions, although it has been used with other toxic alcohols. Ethanol is now regarded as the second choice antidote in those countries with access to the specific ADH blocker